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At the 677 position of the gene, the DNA base cytosine (C) is replaced by thymine (T)
Here, we applied a non-targeted LCMS and LCMS/MS-based peptidomics approach to urine collected from IC/BPS patients and asymptomatic controls to explore differences in the profile of small urinary peptides in this disorder (Fig
A major challenge moving forward lies in distinguishing adaptive metabolic responses from maladaptive fixation, as well as identifying patient subsets most likely to benefit from metabolic intervention
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